Pan-HER Inhibitor Augments Radiation Response in Human Lung and Head and Neck Cancer Models

Francis David M.; Huang Shyhmin; Armstrong Eric A.; Werner Lauryn R.; Hullett Craig; Li Chunrong; Morris Zachary S.; Swick Adam D.; Kragh Michael; Lantto Johan; Kimple Randall J.; Harari Paul M.

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Pan-HER Inhibitor Augments Radiation Response in Human Lung and Head and Neck Cancer Models

机译：Pan-HER抑制剂增强人肺和头颈癌模型的放射反应

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Purpose: Aberrant regulation of the EGF receptor family (EGFR, HER2, HER3, HER4) contributes to tumorigenesis and metastasis in epithelial cancers. Pan-HER represents a novel molecular targeted therapeutic composed of a mixture of six monoclonal antibodies against EGFR, HER2, and HER3.

机译：目的：异常调节EGF受体家族（EGFR，HER2，HER3，HER4）有助于上皮癌的发生和转移。 Pan-HER代表一种新型的分子靶向治疗剂，由六种针对EGFR，HER2和HER3的单克隆抗体组成。

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《Clinical cancer research: an official journal of the American Association for Cancer Research》 |2016年第3期|共11页
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Francis David M.; Huang Shyhmin; Armstrong Eric A.; Werner Lauryn R.; Hullett Craig; Li Chunrong; Morris Zachary S.; Swick Adam D.; Kragh Michael; Lantto Johan; Kimple Randall J.; Harari Paul M.;
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正文语种 eng
中图分类肿瘤学;
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1. Pan-HER Inhibitor Augments Radiation Response in Human Lung and Head and Neck Cancer Models [J] . Francis David M., Huang Shyhmin, Armstrong Eric A., Clinical cancer research: an official journal of the American Association for Cancer Research . 2016,第3期

机译：Pan-HER抑制剂增强人肺和头颈癌模型的放射反应
2. Photon iso-effective dose for cancer treatment with mixed field radiation based on dose-response assessment from human and an animal model: clinical application to boron neutron capture therapy for head and neck cancer [J] . Gonzalez S. J., Pozzi E. C. C., Hughes A. Monti, Physics in medicine and biology. . 2017,第20期

机译：基于人类和动物模型的剂量 - 反应评估，光子肌疗法癌症治疗癌症治疗：对硼中子捕获治疗的临床应用
3. The poly(ADP-Ribose) polymerase inhibitor ABT-888 reduces radiation-induced nuclear EGFR and augments head and neck tumor response to radiotherapy. [J] . Nowsheen S, Bonner JA, Yang ES Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2011,第3期

机译：聚（ADP-核糖）聚合酶抑制剂ABT-888减少了辐射诱导的核EGFR，并增强了头颈部肿瘤对放射疗法的反应。
4. Interaction Between Low Dose-rate Irradiation, Mild Hyperthermia and aNovel Heat Hock Protein Inhibitor, KNK437,in a Human Lung Cancer Cell Line [C] . The 3rd Asian congress on hyperthermic oncology and the 9th Chineses symposium on hyperthermic oncology . 2002

机译：低剂量率辐射，轻度高温与新型热休克蛋白抑制剂KNK 437在人肺癌细胞系中的相互作用
5. Delay to treatment for Latinos diagnosed with lung and head-and-neck cancers: Application of the behavioral model for vulnerable populations. [D] . Scott, Katie L. 2013

机译：拉丁裔诊断为肺癌和头颈癌的治疗延迟：行为模型在弱势人群中的应用。
6. Sym004 a novel anti-EGFR antibody mixture augments radiation response in human lung and head and neck cancers [O] . Shyhmin Huang, Chimera R. Peet, Jarob Saker, -1

机译：Sym004一种新型抗EGFR抗体混合物可增强人肺癌和头颈癌的放射反应
7. Sym004, a Novel Anti-EGFR Antibody Mixture, Augments Radiation Response in Human Lung and Head and Neck Cancers [O] . Shyhmin Huang, Chimera R. Peet, Jarob Saker, 2013

机译：SYM004，一种新型抗EGFR抗体混合物，增加人肺和头部和颈部癌症的辐射响应

Pan-HER Inhibitor Augments Radiation Response in Human Lung and Head and Neck Cancer Models

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