Targeting MDM2 for Treatment of Adenoid Cystic Carcinoma

Warner Kristy A.; Noer Felipe; Acasigua Gerson A.; Martins Manoela D.; Zhang Zhaocheng; McLean Scott A.; Spector Matthew E.; Chepeha Douglas B.; Helman Joseph; Wick Michael J.; Moskaluk Christopher A.; Castilho Rogerio M.; Pearson Alexander T.; Wang Shaomeng; Noer Jacques E.

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Targeting MDM2 for Treatment of Adenoid Cystic Carcinoma

机译：靶向MDM2治疗腺样囊性癌

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Purpose: There are no effective treatment options for patients with advanced adenoid cystic carcinoma (ACC). Here, we evaluated the effect of a new small molecule inhibitor of the MDM2-p53 interaction (MI-773) in preclinical models of ACC.

机译：目的：对于晚期腺样囊性癌（ACC）患者没有有效的治疗选择。在这里，我们评估了ACC临床前模型中MDM2-p53相互作用的新型小分子抑制剂（MI-773）的作用。

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《Clinical cancer research: an official journal of the American Association for Cancer Research》 |2016年第14期|共10页
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Warner Kristy A.; Noer Felipe; Acasigua Gerson A.; Martins Manoela D.; Zhang Zhaocheng; McLean Scott A.; Spector Matthew E.; Chepeha Douglas B.; Helman Joseph; Wick Michael J.; Moskaluk Christopher A.; Castilho Rogerio M.; Pearson Alexander T.; Wang Shaomeng; Noer Jacques E.;
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正文语种 eng
中图分类肿瘤学;
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1. Targeting MDM2 for Treatment of Adenoid Cystic Carcinoma [J] . Warner Kristy A., Noer Felipe, Acasigua Gerson A., Clinical cancer research: an official journal of the American Association for Cancer Research . 2016,第14期

机译：靶向MDM2治疗腺样囊性癌
2. Therapeutic Inhibition of the MDM2-p53 Interaction Prevents Recurrence of Adenoid Cystic Carcinomas [J] . Nor Felipe, Warner Kristy A., Zhang Zhaocheng, Clinical cancer research: an official journal of the American Association for Cancer Research . 2017,第4期

机译：MDM2-P53相互作用的治疗性抑制可防止腺样囊性癌复发
3. Role of chemotherapy and molecularly targeted agents in the treatment of adenoid cystic carcinoma of the lacrimal gland. [J] . Le Tourneau C, Razak AR, Levy C, British journal of ophthalmology . 2011,第11期

机译：化学疗法和分子靶向药物在泪腺腺样囊性癌治疗中的作用。
4. Clinical and Radiological Study of Adenoid Cystic Carcinoma in Salivary gland, Sinonasal Tract and Nasopharyngeal [C] . Bo-Hong SHI, Yong-Mei HUANG, Tao QIN International Conference on Biological Sciences and Technology . 2016

机译：唾液腺腺体囊性癌，SinoNasal道和鼻咽癌的临床和放射学研究
5. Identification and Characterization of Neural-like Cancer Stem Cells in Salivary Adenoid Cystic Carcinoma. [D] . Panaccione, Alexander Colin. 2016

机译：唾液腺样囊性癌中神经样癌干细胞的鉴定与表征。
6. Targeting MDM2 for Treatment of Adenoid Cystic Carcinoma [O] . Kristy A. Warner, Felipe Nör, Gerson A. Acasigua, -1

机译：靶向MDM2治疗腺样囊性癌
7. Targeting MDM2 for Treatment of Adenoid Cystic Carcinoma [O] . Kristy A. Warner, Felipe Nör, Gerson A. Acasigua, 2016

机译：靶向MDM2以治疗腺样囊性癌

Targeting MDM2 for Treatment of Adenoid Cystic Carcinoma

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