A Validated Prognostic Multigene Expression Assay for Overall Survival in Resected Colorectal Cancer Liver Metastases

Balachandran Vinod P.; Arora Arshi; Gonen Mithat; Ito Hiromichi; Turcotte Simon; Shia Jinru; Viale Agnes; Snoeren Nikol; van Hooff Sander R.; Rinkes Inne H. M. Borel; Adam Rene; Kingham T. Peter; Allen Peter J.; DeMatteo Ronald P.; Jarnagin William R.; DAngelica Michael I.

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A Validated Prognostic Multigene Expression Assay for Overall Survival in Resected Colorectal Cancer Liver Metastases

机译：切除大肠癌肝转移的总体生存率的经过验证的预后多基因表达分析

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Purpose: Risk stratification after surgery for colorectal cancer liver metastases (CRLM) is achieved using clinicopathologic variables, however, is of limited accuracy. We sought to derive and externally validate a multigene expression assay prognostic of overall survival (OS) that is superior to clinicopathologic variables in patients with surgically resected CRLM.

机译：目的：使用临床病理学变量可实现大肠癌肝转移（CRLM）术后风险分层，但是准确性有限。我们寻求获得并在外部验证总生存期（OS）的预后的多基因表达检测方法，该方法优于手术切除的CRLM患者的临床病理学变量。

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《Clinical cancer research: an official journal of the American Association for Cancer Research》 |2016年第10期|共8页
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Balachandran Vinod P.; Arora Arshi; Gonen Mithat; Ito Hiromichi; Turcotte Simon; Shia Jinru; Viale Agnes; Snoeren Nikol; van Hooff Sander R.; Rinkes Inne H. M. Borel; Adam Rene; Kingham T. Peter; Allen Peter J.; DeMatteo Ronald P.; Jarnagin William R.; DAngelica Michael I.;
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正文语种 eng
中图分类肿瘤学;
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1. A Validated Prognostic Multigene Expression Assay for Overall Survival in Resected Colorectal Cancer Liver Metastases [J] . Balachandran Vinod P., Arora Arshi, Gonen Mithat, Clinical cancer research: an official journal of the American Association for Cancer Research . 2016,第10期

机译：切除大肠癌肝转移的总体生存率的经过验证的预后多基因表达分析
2. Prognostic Similarities and Differences in Optimally Resected Liver Metastases and Peritoneal Metastases From Colorectal Cancers [J] . Elias Dominique, Faron Matthieu, Iuga Bogdan Stan, Annals of Surgery . 2015,第1期

机译：从结肠直肠癌最佳切除肝转移和腹膜转移中的预后相似性和差异
3. A Comprehensive MicroRNA Expression Profile of Liver and Lung Metastases of Colorectal Cancer with Their Corresponding Host Tissue and Its Prognostic Impact on Survival [J] . Mathieu Pecqueux, Isabell Liebetrau, Wiebke Werft, International Journal of Molecular Sciences . 2016,第10期

机译：结肠癌及其相应宿主组织肝，肺转移瘤的microRNA表达谱及其对生存率的影响
4. Survival Benefit of Pelvic Exenteration for Locally Advanced Colorectal Cancer with Lymph Node Metastases [C] . J. Hida, T. Yoshifuji, F. Sugiura, International Society of University Colon and Rectal Surgeons . 2008

机译：淋巴结转移盆腔盆腔盆腔盆腔出生的生存效益
5. Abnormal expression of proprotein convertases PC5/6 but not NARC-1 in human colorectal cancer and their liver metastases. [D] . Benay, Cassandre E. 2007

机译：在人类大肠癌及其肝转移中，前蛋白转化酶PC5 / 6而非NARC-1的异常表达。
6. A validated prognostic multigene expression assay for overall survival in resected colorectal cancer liver metastases [O] . Vinod P. Balachandran, Arshi Arora, Mithat Gönen, -1

机译：经过验证的多基因表达预后分析可用于切除大肠癌肝转移的总体生存期
7. A Validated Prognostic Multigene Expression Assay for Overall Survival in Resected Colorectal Cancer Liver Metastases [O] . Vinod P. Balachandran, Arshi Arora, Mithat Gönen, 2016

机译：切除结直肠癌肝转移中的整体存活的验证的预后多烯表达测定

A Validated Prognostic Multigene Expression Assay for Overall Survival in Resected Colorectal Cancer Liver Metastases

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