Safety and efficacy of transepithelial crosslinking (C3-R/CXL).

摘要

Baiocchi et al. measured stromal riboflavin using a 0.1% riboflavin-20% dextran solution and concluded there are concerns about safety and efficacy of transepi-thelial crosslinking. Their study has several limitations:The authors admit they have "theoretical indicators" of safety and efficacy. These should not be misinterpreted by the ophthalmic community as a benchmark for future riboflavin penetration studies. More work is needed in this area.