Mitomycin-C in photorefractive keratectomy

摘要

In their article on intracameral injection of moxiflox-acin in the prevention of endophthalmitis, Matsuura et al.1 report 8 cases of endophthalmitis in the control group of 15 958 and 3 cases of endophthalmitis in the treatment group of 18 794. They report an incidence of 0.051% (1 in 1955) in the control group and of 0.015% (1 in 6265) in the treatment group, suggesting a statistically significant difference (P = .037). I would like to point out that there are inaccuracies in their statistical analysis, some of which are significant. First, the incidence in the control group should be 0.050% (8/15 958 = 0.05013%, not 0.051%) and in the treatment group, 0.016% (3/18 794 = 0.01596%, not 0.015%), albeit these are small errors.