Incorporation of Next-Generation Sequencing into Routine Clinical Care to Direct Treatment of Head and Neck Squamous Cell Carcinoma

Chau Nicole G.; Li Yvonne Y.; Jo Vickie Y.; Rabinowits Guilherme; Lorch Jochen H.; Tishler Roy B.; Margalit Danielle N.; Schoenfeld Jonathan D.; Annino Don J.; Goguen Laura A.; Thomas Tom; Becker Hailey; Haddad Tyler; Krane Jeffrey F.; Lindeman Neal I.; Shapiro Geoffrey I.; Haddad Robert I.; Hammerman Peter S.

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Incorporation of Next-Generation Sequencing into Routine Clinical Care to Direct Treatment of Head and Neck Squamous Cell Carcinoma

机译：将下一代测序纳入常规临床护理以直接治疗头颈部鳞状细胞癌

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Purpose: The clinical impact of next-generation sequencing (NGS) in patients with head and neck squamous cell carcinoma (HNSCC) has not been described. We aimed to evaluate the clinical impact of NGS in the routine care of patients with HNSCC and to correlate genomic alterations with clinical outcomes.

机译：目的：尚未描述下一代测序（NGS）对头颈部鳞状细胞癌（HNSCC）患者的临床影响。我们旨在评估NGS在HNSCC患者常规护理中的临床影响，并将基因组改变与临床结果相关联。

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《Clinical cancer research: an official journal of the American Association for Cancer Research》 |2016年第12期|共11页
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Chau Nicole G.; Li Yvonne Y.; Jo Vickie Y.; Rabinowits Guilherme; Lorch Jochen H.; Tishler Roy B.; Margalit Danielle N.; Schoenfeld Jonathan D.; Annino Don J.; Goguen Laura A.; Thomas Tom; Becker Hailey; Haddad Tyler; Krane Jeffrey F.; Lindeman Neal I.; Shapiro Geoffrey I.; Haddad Robert I.; Hammerman Peter S.;
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中图分类肿瘤学;
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1. Incorporation of Next-Generation Sequencing into Routine Clinical Care to Direct Treatment of Head and Neck Squamous Cell Carcinoma [J] . Chau Nicole G., Li Yvonne Y., Jo Vickie Y., Clinical cancer research: an official journal of the American Association for Cancer Research . 2016,第12期

机译：将下一代测序纳入常规临床护理以直接治疗头颈部鳞状细胞癌
2. Curative treatment of head and neck squamous cell carcinoma Organ preservation strategies in clinical routine in German-speaking countries [J] . Kurzweg T., Kimmeyer J., Knecht R., HNO . 2016,第7期

机译：头颈部鳞状细胞癌的治愈性治疗德语国家的临床常规中的器官保存策略
3. Comprehensive T-cell immunophenotyping and next-generation sequencing of human papillomavirus (HPV)-positive and HPV-negative head and neck squamous cell carcinomas [J] . Poropatich Kate, Fontanarosa Joel, Swaminathan Suchitra, Journal of Pathology: Journal of the Pathological Society of Great Britain and Ireland . 2017,第3期

机译：人乳头瘤病毒（HPV）综合T细胞免疫蛋白型和下一代测序 - 阳性和HPV阴性头部和颈鳞状细胞癌
4. Up-Regulation of Enhancer of Zeste Homolog 2 Is Associated Positively With Cyclin Dl Overexpression and Poor Clinical Outcome in Head and Neck Squamous Cell Carcinoma [C] . Wei Cao, Zhien Feng, Zhibin Cui, Academic Committee conference of Shanghai key lab of stomatology . 2011

机译：Zeste同源2的增强子的上调与Cyclin Dl过度表达和头颈部鳞状细胞癌的不良临床结果呈正相关。
5. PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma. [D] . 野﨑, 結 2019

机译：PD-L1特异性辅助性T细胞表现出有效的抗肿瘤反应：针对头颈部鳞状细胞癌中PD-L1的癌症免疫疗法的新策略。
6. Investigating the Feasibility of Targeted Next-Generation Sequencing to Guide the Treatment of Head and Neck Squamous Cell Carcinoma [O] . Sun Min Lim, Sang Hee Cho, In Gyu Hwang, 2019

机译：研究靶向新一代测序技术指导头颈部鳞状细胞癌治疗的可行性
7. Investigating the Feasibility of Targeted Next-Generation Sequencing to Guide the Treatment of Head and Neck Squamous Cell Carcinoma [O] . Sun Min Lim, Sang Hee Cho, In Gyu Hwang, 2019

机译：研究靶向下一代测序的可行性，以指导头部鳞状细胞癌的治疗

Incorporation of Next-Generation Sequencing into Routine Clinical Care to Direct Treatment of Head and Neck Squamous Cell Carcinoma

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