Gas chromatographic method for the determination of toluidines in spiked urine samples

摘要

A capillary gas-chromatographic method was developed for the analysis of a mixture of toluidines in urine. The method is based on the extraction of toluidines with toluene and derivatisation with heptafluorobutyric anhydride to form a product for electron capture detection. The procedure gave a Linear response at concentrations of 0.02-0.20 mu g/ml with sufficient reproducibility. The method is simple, requires little sample pretreatment and is being considered for biomonitoring workers exposed to toluidines. (C) 2000 Elsevier Science B.V. All rights reserved. [References: 20]