Clinical and Pathological Study on Patients With Primary Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis With Renal Immune Complex Deposition

摘要

Background: Traditionally, antineutrophil cytoplasmic autoantibody-associated vasculitis (AAV) is histologically characterized by pauci-immune glomerulonephritis. However, more and more literature has reported immune complex (IC) deposits to be found in renal specimen from patients with AAV. The role that these IC deposits play in the development of AAV, as well as their clinical and pathological significance, is worthy of studying.