Synthesis and crystal structure of novel N-acyl-N '-dichloroacetyl-6,7-dichloro-1,2,3,4-tetrahydroquinoxalines derivatives

摘要

A two-step sequence was developed for synthesising different disubstituted 6,7-dichloro-1,2,3,4-tetrahydroquinoxalines without blocking the reactive centres. N-dichloroacetyl-6,7-dichloro-1,2,3,4-tetrahydroquinoxaline was prepared from 6,7-dichloro-1,2,3,4-tetrahydroquinoxaline and dichloroacetyl chloride giving N-acyl-N'-dichloroacetyl-6,7-dichloro-1,2,3,4-tetrahydroquinoxalines. The structures of all the compounds were characterised by IR, H-1 NMR, C-13 NMR, and elemental analysis. The structure was determined by X-ray crystallography.