Synthesis of 6-t rifluoromethyl derivatives of 2-arylamino-4-(pyridin-3-yl) pyrimidines

Terentjeva S.; Muceniece D.; Lusis V.

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Synthesis of 6-t rifluoromethyl derivatives of 2-arylamino-4-(pyridin-3-yl) pyrimidines

机译：2-芳基氨基-4-（吡啶-3-基）嘧啶的6-叔氟甲基衍生物的合成

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摘要

The 6-trifluoromethyl derivative of a well known tyrosine kinase inhibitor, nilotinib, as well as some novel 6-trifluoromethyl substituted 2-arylamino-4-(pyridin-3-yl) pyrimidines were synthesised.

机译：合成了众所周知的酪氨酸激酶抑制剂尼洛替尼的6-三氟甲基衍生物，以及一些新颖的6-三氟甲基取代的2-芳基氨基-4-（吡啶-3-基）嘧啶。

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《Journal of chemical research: reviews and research papers from all branches of chemistry》 |2015年第4期|共3页
作者
Terentjeva S.; Muceniece D.; Lusis V.;
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正文语种 eng
中图分类化学;
关键词
N-aryl guanidines; 4; 4; 4-trifluoro-1-(pyridin-3-yl)butane-1; 3-dione; 4-(pyridin-3-yl) pyrimidines; 6-trifluoromethyl pyrimidines; 2-arylamino-4-(pyridin-3-yl) pyrimidines;

机译：N-芳基胍;4;4;4-三氟-1-（吡啶-3-基）丁烷-1;3-二酮;4-（吡啶-3-基）嘧啶;6-三氟甲基嘧啶;2-芳基氨基- 4-（吡啶-3-基）嘧啶;

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1. Synthesis of 6-t rifluoromethyl derivatives of 2-arylamino-4-(pyridin-3-yl) pyrimidines [J] . Terentjeva S., Muceniece D., Lusis V. Journal of chemical research: reviews and research papers from all branches of chemistry . 2015,第4期

机译：2-芳基氨基-4-（吡啶-3-基）嘧啶的6-叔氟甲基衍生物的合成
2. Synthesis and characterization of antibacterial 2-(pyridin-3-yl)-1H-benzo[d]imidazoles and 2-(pyridin-3-yl)-3H-imidazo[4,5-b]pyridine derivatives [J] . Mallemula Venkata Ramakrishna, Sanghai Niraj Nemichand, Himabindu V., Research on Chemical Intermediates . 2015,第4期

机译：抗菌2-（吡啶-3-基）-1H-苯并[d]咪唑和2-（吡啶-3-基）-3H-咪唑并[4,5-b]吡啶衍生物的合成与表征
3. Blue iridium(III) complexes with high internal quantum efficiency based on 4-(pyridin-3-yl)pyrimidine derivative and their electroluminescent properties [J] . Dyes and Pigments . 2020,第期

机译：基于4-（吡啶-3-基）嘧啶衍生物及其电致发光性能，具有高内部量子效率的蓝色铱星（III）复合物
4. Catalytic performance of CuO@SiO2 for one-pot synthesis of pyrimidine derivative,ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate [C] . A H Cahyana, S P Sari, B Ardiansah International Symposium on Current Progress in Functional Materials . 2019

机译：CuO / 2-oxo-4-苯基-1,2,3,4-四氢嘧啶-5-羧酸乙烯基二罐合成CuO / 2-氧代-4-苯基-1,2,3,4-四氢嘧啶-5-羧酸酯的催化性能
5. Control of Pyrimidine Biosynthesis in Pseudomonas aurantiaca by Pyrimidines [D] . Domakonda, Anvesh. 2018

机译：用嘧啶对吡啶基菌根的嘧啶生物合成的控制
6. Heterocyclization of polarized system: synthesis antioxidant and anti-inflammatory 4-(pyridin-3-yl)-6-(thiophen-2-yl) pyrimidine-2-thiol derivatives [O] . Wesam S. Shehab, Magda H. Abdellattif, Samar M. Mouneir 2018

机译：极化系统的杂环化：合成抗氧化剂和抗炎药4-（吡啶-3-基）-6-（噻吩-2-基）嘧啶-2-硫醇衍生物
7. Synthesis and characterization of antibacterial 2-(pyridin-3-yl)-1-benzoimidazoles and 2-(pyridin-3-yl)-3-imidazo4,5-pyridine derivatives [O] . 2015

机译：抗菌2-（吡啶-3-基）-1-苯并咪唑和2-（吡啶-3-基）-3-咪唑并4,5-吡啶衍生物的合成与表征

Synthesis of 6-t rifluoromethyl derivatives of 2-arylamino-4-(pyridin-3-yl) pyrimidines

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