Regio- and stereoselective synthesis of α,β-dehydro-β-amino esters

摘要

A facile method for the regio- and stereoselective synthesis of α,β-dehydro-β-amino esters from acetates of Baylis-Hillman adducts with amines was reported. In the absence of any solvent and catalyst, the present strategy works well for a series of electron deficient and electron rich aromatic amines as well as aliphatic ones.