1,1'-bis-methyl-3, 3-methylenebisimidazolium dichloride as an efficient phase transfer catalyst for ring opening of epoxides using SCN- and N _3 - in water

摘要

An efficient synthesis of β-azido alcohols and β-hydroxy thiocyanates has been achieved by ring opening of epoxides using 1,1'-bis-methyl-3, 3-methylene-bisimidazolium dichloride as a phase transfer catalyst at room temperature in water. The reaction is regioselective and afforded the corresponding products in moderate to excellent yields.