Synthesis, characterisation and antimicrobial activity 1-aminopyrimidine- 2(1H)-thione and its Co(II), Ni(II), Pd(II) and Pt(II) complexes

摘要

Metal complexes of 1-aminopyrimidine-2(1H)-thione were prepared from acetate salts of Co(II), Ni(II), Pd(II) and Pt(II) in methanol. Electronic spectral data and magnetic moment measurements suggest mononuclear square planar geometrical structures for the metal complexes. The ligand and all the metal complexes were evaluated for their antimicrobial activity. The newly synthesised ligand and the Co(II) complex showed moderate activity against all tested bacteria and yeast strains.