Recycling and Reuse of a Polymer-Supported Scavenger for Amine Sequestration

摘要

The regeneration and reuse of a supported scavenger I for amine sequestration has been achieved up to three times without significant loss of activity. The scavenging process between the aldehyde resin 1 and a range of amines has been investigated in detail to determine the scope of this scavenger. Its application for the rapid purification of a small library of secondary amines 7a-J has also been demonstrated, and it has been shown that the large excess of scavenger resin used can be recovered and recycled, making this a more cost-effective process.