Rapid Combinatorial Access to a Library of 1,5-Disubstituted-3-indole-N-alkylacetamides as CB2 Receptor Ligands

Serena Pasquini; Claudia Mugnaini; Antonella Brizzi

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Rapid Combinatorial Access to a Library of 1,5-Disubstituted-3-indole-N-alkylacetamides as CB2 Receptor Ligands

机译：快速组合访问作为CB2受体配体的1,5-二取代-3-吲哚-N-烷基乙酰胺库

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The indole ring system represents a "privileged structure" in drug discovery. The number of bioactive compounds containing this ring system is so vast that the complete range of their biological activities can be hardly classified.

机译：吲哚环系统代表药物发现中的“特权结构”。包含该环系统的生物活性化合物的数量如此之多，以至于几乎无法对其生物活性的整个范围进行分类。

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《Journal of combinatorial chemistry》 |2009年第5期|共4页
作者
Serena Pasquini; Claudia Mugnaini; Antonella Brizzi;
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正文语种 eng
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1. Rapid Combinatorial Access to a Library of 1,5-Disubstituted-3-indole-N-alkylacetamides as CB2 Receptor Ligands [J] . Serena Pasquini, Claudia Mugnaini, Antonella Brizzi Journal of combinatorial chemistry . 2009,第5期

机译：快速组合访问作为CB2受体配体的1,5-二取代-3-吲哚-N-烷基乙酰胺库
2. Combinatorial peptide ligand library plasma treatment: Advantages for accessing low-abundance proteins [J] . Olivia Beseme, Marie Fertin, Hervé Drobecq, ELECTROPHORESIS . 2010,第16期

机译：组合肽配体库血浆处理：获得低丰度蛋白质的优势
3. Combinatorial peptide ligand library plasma treatment: Advantages for accessing low-abundance proteins. [J] . Beseme O, Fertin M, Drobecq H, Electrophoresis: The Official Journal of the International Electrophoresis Society . 2010,第16期

机译：组合肽配体库血浆处理：获得低丰度蛋白质的优势。
4. THE ROLE OF ANANDAMIDE AND RELATED FATTY ACID ETHANOLAMIDES AS ENDOGENOUS LIGANDS FOR THE CB1 AND CB2 CANNABINOID RECEPTORS [C] . Christian C. Felder, Amie Nielsen, Eileen M. Briley, International Washington Spring Symposium . 1996

机译：Anandamide和相关脂肪酸乙醇酰胺作为CB1和CB2大麻素受体的内源配体的作用
5. Part I. Hz166, a novel γ-aminobutyric acid (A) receptor subtype-selective ligand active against neuropathic pain Part II. The first enantiospecific, stereospecific total synthesis of the C-19 methyl substituted sarpagine indole alkaloids 19(S), 20(R), 19-(S),20(R)dihydroperaksine-17-al and peraksine Part III. Application of metal-carbenoid chemistry and Brönsted acid mediated cyclization of enaminones for the rapid and efficient access to the tetracyclic (ABCE) skeleton of the Strychnos alkaloids contained in bisindole alkaloids [D] . Edwankar, Rahul V. 2010

机译：第I部分：Hz166，一种新型的对神经性疼痛有活性的γ-氨基丁酸（A）受体亚型选择性配体。 C-19甲基取代的沙雷帕金吲哚生物碱19（S），20（R），19-（S），20（R）dihydroperaksine-17-al和peraksine第三部分的第一个对映体特异性，立体定向全合成。金属类固醇化学和布朗斯台德酸介导的烯胺酮环化的应用，用于快速有效地获取双吲哚生物碱中马兜铃生物碱的四环（ABCE）骨架
6. Seamless Bead to Microarray Screening: Rapid Identification of the Highest Affinity Protein Ligands From Large Combinatorial Libraries [O] . John M. Astle, Levi S. Simpson, Yong Huang, -1

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7. Seamless Bead to Microarray Screening: Rapid Identification of the Highest Affinity Protein Ligands from Large Combinatorial Libraries [O] . Astle John M., Simpson Levi S., Huang Yong, 2010

机译：无缝珠子到微阵列筛选：大型组合图书馆中最高亲和力蛋白配体的快速鉴定

Rapid Combinatorial Access to a Library of 1,5-Disubstituted-3-indole-N-alkylacetamides as CB2 Receptor Ligands

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