Reactions with 3-amino-5-trifluoromethyl[1,2,4]triazole: A convenient route to fluorinated triazole[1,5-c]thiadiazine, triazolo[1,5-a]triazine, thiazoles and thiadiazoles

摘要

The reaction of 3-amino-5-trifluoromethyl[1,2,4]triazole with carbon disulfide or phenyl isothiocyanate followed by heterocyclization with haloketones, haloesters and hydrazonoyl halides has been utilized for the synthesis of the title compounds; chemical and spectroscopic evidence for the suggested structures of the new compounds and a sequence leading to their formation are discussed. [References: 17]