Synthesis of 2,5- and 2,6-di-t-butyl-4-halo- or-4-methoxy-phenols using silica, lithium perchlorate and lithium bromide as neutral catalysts

摘要

When a mixture of 4-halo- or 4-methoxy-phenol and excess of t-butyl chloride in the presence of neutral catalyst such as silica or lithium perchlorate or lithium bromide was refluxed, 2,5-and 2,6-di-t-butyl-4-halo or 4-methoxy phenols were obtained in good yields. [References: 7]