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Reliability of quantitative and qualitative tests to identify heterozygotes carrying severe or mild G6PD deficiency.

机译:定量和定性测试可确定携带严重或轻度G6PD缺乏症的杂合子的可靠性。

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摘要

OBJECTIVES: To determine if the qualitative test (cytochemical) is more reliable than the quantitative test (differential pH-metry) in identifying heterozygous G6PD- subjects. DESIGN AND METHODS: Identification of heterozygous G6PD- subjects was done by the measurement of G6PD activity and by a cytochemical test. RESULTS: A cytochemical test is more sensitive than differential pH-metry to identify heterozygous G6PD- subjects. CONCLUSIONS: A cytochemical test is a reliable method for mass screening for G6PD deficiency to identify G6PD- heterozygotes.
机译:目的:确定在鉴定杂合G6PD-受试者方面,定性测试(细胞化学)是否比定量测试(差示pH测量)更可靠。设计和方法:通过测量G6PD活性和细胞化学测试鉴定杂合G6PD-受试者。结果:细胞化学测试比鉴别pH值测定更灵敏,可以识别杂合G6PD-受试者。结论:细胞化学检测是对G6PD缺乏症进行大规模筛查以鉴定G6PD-杂合子的可靠方法。

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