Microbiological transformations. Part 14. Microbiological transformations of derivatives and open-chain analogues of 1,2,3,4-tetrahydroisoquinoline with the fungus Cunninghamella elegans

摘要

Incubation of N-benzoyl- and 1-methyl-N-benzoyl-1,2,3,4-tetrahydroisoquinolines with the mycelium of the fungus Cunninghamella elegans results in both benzylic hydroxylation and the formation of phenolic products; the 2- and 3-methyl substituted analogues gave products arising from C-1 hydroxylation.