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首页> 外文期刊>Journal of clinical psychopharmacology >Generalized action myoclonus associated with escitalopram in a patient with mixed dementia.
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Generalized action myoclonus associated with escitalopram in a patient with mixed dementia.

机译:混合性痴呆患者中与艾司西酞普兰相关的全身性肌阵挛。

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摘要

Escitalopram is the S-stereoisomer of citalopram and a selective serotonin reuptake inhibitor (SSRI). Studies have shown that escitalopram and citalopram produce different effects, possibly because of a lack of contrasting action for R-citalopram. However, side effects are quite similar for the 2 drugs and certainly include serotonin toxicity and other effects.-We report the case of 78-year-old woman presenting with generalized action myoclonus possibly related to escitalopram intake. Her medical history was significant for coronary disease treated with percutaneous coronary intervention with stenting, previous cholecystectomy, previous isteroannessiectomy for endo-metrial cancer, insulin-dependent diabetes, hypertension, nonalcoholic hepatic steatosis, and previous left hemispheric transient ischemic attack.
机译:Escitalopram是Citalopram的S-立体异构体,是选择性5-羟色胺再摄取抑制剂(SSRI)。研究表明,依他普仑和西酞普兰产生不同的作用,可能是由于缺乏对R-西酞普兰的对比作用。但是,这两种药物的副作用非常相似,并且肯定包括5-羟色胺毒性和其他作用。-我们报道了一名78岁女性,其全身活动性肌阵挛可能与艾司西酞普兰的摄入有关。她的病史对于通过经皮冠状动脉支架置入术,先前的胆囊切除术,先前的子宫内膜切除术治疗子宫内膜癌,胰岛素依赖型糖尿病,高血压,非酒精性肝脂肪变性和先前的左半球短暂性脑缺血发作治疗冠状动脉疾病具有重要意义。

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