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首页> 外文期刊>Clinical journal of the American Society of Nephrology: CJASN >The Role of Time-Limited Trials in Dialysis Decision Making in Critically Ill Patients
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The Role of Time-Limited Trials in Dialysis Decision Making in Critically Ill Patients

机译:限时试验在重症患者透析决策中的作用

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摘要

Technologic advances, such as continuous RRT, provide lifesaving therapy for many patients. AKI in the critically ill patient, a fatal diagnosis in the past, is now often a survivable condition. Dialysis decision making for the critically ill patient with AKI is complex. What was once a question solely of survival now is nuanced by an individual's definition of quality of life, personal values, and short and long term prognoses. Clinical evaluation of AKI in the critically ill is multifaceted. Treatment decision making requires consideration of the natural evolution of the patient's AKI within the context of the global prognosis. Situations are often marked by prognostic uncertainty and clinical unknowns. In the face of these uncertainties, establishment of patient-directed therapies is imperative. A time limited trial of continuous RRT in this setting is often appropriate but difficult to execute. Using patient preferences as a clinical guide, a proper time limited trial requires assessment of prognosis, elicitation of patient values, strong communication skills, clear documentation, and often, appropriate integration of palliative care services. A well conducted time limited trial can avoid interprofessional conflict and provide support for the patient, family, and staff.
机译:持续的RRT等技术进步为许多患者提供了挽救生命的疗法。重症患者的AKI过去是致命的诊断,现在通常是可以存活的疾病。 AKI重症患者的透析决策非常复杂。现在,曾经仅是生存问题的一个问题已被个人对生活质量,个人价值观以及短期和长期预后的定义所影响。重症AKI的临床评估是多方面的。在制定治疗决策时,需要考虑整体预后情况下患者AKI的自然演变。情况通常以预后不确定和临床未知为特征。面对这些不确定性,必须建立以患者为导向的疗法。在这种情况下进行连续RRT的有时间限制的试验通常是适当的,但难以执行。以患者的喜好作为临床指南,适当的限时试验需要评估预后,确定患者的价值观,较强的沟通能力,清晰的文档记录,以及经常适当地整合姑息治疗服务。进行良好的时间有限的试验可以避免专业间的冲突,并为患者,家人和员工提供支持。

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