Reactivity of the Monoterpenoid Nerol with p-Toluenesulfonic and Chlorosulfonic Acids:Selective Syntheses of alpha-Terpineol and alpha-Cyclogeraniol An Activity for the Undergraduate Organic Lab

摘要

The monoterpenoids are a large group of naturally occurring compounds that have mainly been isolated from higher plants,algae,marine organisms,insects,and some vertebrate animals (1).Members of this chemical family have been used since antiquity in herbal and folk medicine,for food flavoring and preservation,and as ingredients of perfumes and soaps (1-3).Although monoterpenoids would provide good examples for structure elucidation and mechanistic studies,the undergraduate curriculum rarely provides a chance to study this fascinating group of natural products (1).