Alkaloids:Strychnine,Codeine,Heroin,and Morphine

摘要

The featured molecules this month come from the article "The Conversion of Carboxylic Acids to Ketones:A Repeated Discovery" by John W.Nicholson and Alan D.Wilson (pages 1362-1366).The authors describe the repeated "discovery" of this reaction and illustrate its central role in Woodward's total synthesis of strychnine.