Micro wave-Assisted Carbonyl Chemistry for the Undergraduate Laboratory

摘要

Microwave-assisted synthesis continues to make significant headway into mainstream of organic chemistry, as demonstrated by several recent reviews on the topic (1). Advantages of this technology have been realized throughout the length and breadth of the field, from total synthesis (2) to synthetic methodology (3) and from industrial research and development (4) to drug discovery (5). A literature search using the concepts of "microwave" and "organic synthesis" returns more than 500 journal articles over the past five years, more than twice the number, in the previous five-year period (1998-2002). Similarly, the rate of patent publication in this area has more than tripled over the same time periods.