The Synthesis and Crystal Structure of Cbz-[(1R,2S)-ACPC]_3-OH: A Tripeptide Derived from the β-Amino Acid (1R,2S)-Cispentacin

摘要

Crystals of the tripeptide Cbz-[(1R,2S)- ACPC]_3-OH 4, derived from the β-amino acid (1R,2S)-2- aminocyclopentanecarboxylic acid, were synthesised and studied by X-ray diffraction. Tripeptide 4 crystallizes in the orthorhombic space group P 2_12_12_1 with cell parameters of a = 7.8957(1) ?, b = 12.9289(2) ?, c = 24.7850(4) ?, V = 2530.12(6) ?~3 and Z = 4. Adjacent molecules are linked by a series of N-H…O=C and O-H···O=C hydrogen bonds to form a double tape-like arrangement.