Structure determination of 8-benzyl-5-phenyl-3-oxa-4,8-diaza-tricyclo[5.2. 1.0 ~(2,6)]dec-4-ene and 1-(9-Ethoxy-5-phenyl-3-oxa-4,8-diaza-tricyclo[5. 2.1.0 ~(2,6)]dec-4-en-8-yl)-ethanone: Their synthesis, chemical relationship and comparison with similar compounds

摘要

The molecular and crystal structures of 8-benzyl-5-phenyl-3-oxa-4,8-diaza- tricyclo[5.2.1.0 ~(2,6)]dec-4-ene 11a and 1-(9-ethoxy-5-phenyl-3-oxa-4,8- diaza-tricyclo[5.2.1.0 ~(2,6)]dec-4-en-8-yl)-ethanone 13a have been XRD determined. The compounds crystallize in the monoclinic system with space groups P2 _1 and P2 _1/c, respectively. The synthesis and chemical relationship between the two compounds are reported and their structures are compared with others of the aza-norbornene and isoxazoline families. Graphical Abstract: The molecular and crystal structures of 8-benzyl-5-phenyl-3-oxa-4,8- diaza-tricyclo[5.2.1.0 ~(2,6)]dec-4-ene 11a and 1-(9-ethoxy-5-phenyl-3- oxa-4,8-diaza-tricyclo[5.2.1.0 ~(2,6)]dec-4-en-8-yl)-ethanone 13a have been XRD determined.[Figure not available: see fulltext.]