Associations of Urinary Uromodulin with Clinical Characteristics and Markers of Tubular Function in the General Population

摘要

Background and objectives Allelic variants in UMOD, the gene coding for uromodulin, are associated with rare tubulointerstitial kidney disorders and risk of CKD and hypertension in the general population. The factors associated with uromodulin excretion in the normal population remain largely unknown, and were therefore explored in this study.