Increased extent of myocardial fibrosis in genotyped hypertrophic cardiomyopathy with ventricular tachyarrhythmias

Fujita Takashi; Konno Tetsuo; Yokawa Junichiro; Masuta Eiichi; Nagata Yoji; Fujino Noboru; Funada Akira; Hodatsu Akihiko; Kawashiri Masa-Aki; Yamagishi Masakazu; Hayashi Kenshi

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Increased extent of myocardial fibrosis in genotyped hypertrophic cardiomyopathy with ventricular tachyarrhythmias

机译：基因型肥厚型心肌病伴室性快速性心律失常的心肌纤维化程度增加

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Background: Occurrence of malignant ventricular tachyarrhythmias such as ventricular tachycardia and fibrillation (VT/VF) in hypertrophic cardiomyopathy (HCM) can be related to the extent of myocardial fibrosis. Although late gadolinium enhancement (LGE) on cardiovascular magnetic resonance (CMR) imaging has been used to detect myocardial fibrosis, few data exist regarding relationships between CMR-determined myocardial fibrosis and VT/VF in genotyped HCM populations.

机译：背景：肥厚型心肌病（HCM）中发生室性心律失常，例如室性心动过速和房颤（VT / VF）可能与心肌纤维化程度有关。尽管心血管磁共振（CMR）影像学上的晚期g增强（LGE）已用于检测心肌纤维化，但关于基因型HCM人群中由CMR测定的心肌纤维化与VT / VF之间关系的数据很少。

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来源
《Journal of cardiology》 |2015年第2期|共6页
作者
Fujita Takashi; Konno Tetsuo; Yokawa Junichiro; Masuta Eiichi; Nagata Yoji; Fujino Noboru; Funada Akira; Hodatsu Akihiko; Kawashiri Masa-Aki; Yamagishi Masakazu; Hayashi Kenshi;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
Hypertrophic cardiomyopathy; Ventricular arrhythmia; Myocardial fibrosis; Magnetic resonance imaging;

机译：肥厚型心肌病;室性心律失常;心肌纤维化;磁共振成像;

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专利

1. Increased extent of myocardial fibrosis in genotyped hypertrophic cardiomyopathy with ventricular tachyarrhythmias [J] . Fujita Takashi, Konno Tetsuo, Yokawa Junichiro, Journal of cardiology . 2015,第1a2期

机译：基因型肥厚型心肌病伴室性快速性心律失常的心肌纤维化程度增加
2. Association of myocardial fibrosis, electrocardiography and ventricular tachyarrhythmia in hypertrophic cardiomyopathy: a delayed contrast enhanced MRI study [J] . Deborah H. Kwon, Randolph M. Setser, Zoran B. Popovi?, The International Journal of Cardiovascular Imaging . 2008,第6期

机译：肥厚型心肌病中心肌纤维化，心电图和室性心律失常的关联：增强MRI的延迟对比研究
3. Myocardial fibrosis in patients with symptomatic obstructive hypertrophic cardiomyopathy: correlation with echocardiographic measurements, sarcomeric genotypes, and pro-left ventricular hypertrophy polymorphisms involving the renin-angiotensin-aldosterone system. [J] . Blauwet LA, Ackerman MJ, Edwards WD Cardiovascular pathology: the official journal of the Society for Cardiovascular Pathology . 2009,第5期

机译：有症状的梗阻性肥厚型心肌病患者的心肌纤维化：与超声心动图测量，肌节型基因型和涉及肾素-血管紧张素-醛固酮系统的左心室肥大多态性相关。
4. Differences between ventricular tachyarrhythmias for patients with coronary artery disease and dilated cardiomyopathy [C] . Casaleggio A., Rossi P., Malavasi V., Computers in Cardiology, 2008 . 2008

机译：冠心病和扩张型心肌病患者室性心律失常的区别
5. Experimental and analytical investigation of flow pressure transients in left ventricular ejection with applications to hypertrophic cardiomyopathy [D] . Hay, Andrew Stuart 1995

机译：肥厚型心肌病在左心室射血中流动压力瞬变的实验和分析研究
6. Extent of late gadolinium enhancement detected by cardiovascular magnetic resonance correlates with the inducibility of ventricular tachyarrhythmia in hypertrophic cardiomyopathy [O] . Stephan Fluechter, Jürgen Kuschyk, Christian Wolpert, 2010

机译：心血管磁共振检测到的晚期g增强程度与肥厚型心肌病的室速性心律失常的诱导能力有关
7. Increased extent of myocardial fibrosis in genotyped hypertrophic cardiomyopathy with ventricular tachyarrhythmias [O] . Fujita Takashi, Konno Tetsuo, Yokawa Junichiro, 2015

机译：基因型肥厚型心肌病伴室性快速性心律失常的心肌纤维化程度增加

Increased extent of myocardial fibrosis in genotyped hypertrophic cardiomyopathy with ventricular tachyarrhythmias

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