EXPLORATION OF INTESTINAL ABSORPTION AND RENAL EXCRETION OF CALCIUM BY STABLE STRONTIUM TEST IN CAMELS (Camelus dromedarius)

摘要

The present study was undertaken to evaluate the intestinal calcium absorption using stable strontium (Sr) as a surrogate marker in five newborn camels. Two tests were performed with an interval of 10 days for calculating the within-animals variationof plasma Sr (CV%). The area under the concentration-time curve (AUC~(0-300)) 5 hours after an oral SrCI_2 load of 4.1 mmol was 10.11 ± 0.542 mmol/L~(-1)/min. The within-animals CV% of AUC~(0-300) was 11.6. In our animals, plasma calcium (Ca) and phosphorus (Pi) levels were not significantly modified by Sr load. The fractional Sr excretion 5 hours after oral load in percentage of Sr dose administered was 1.03 ± 0.22% and Sr renal clearance was 4.12 ± 0.51 mL/min. Sr test had no significant effect upon renal excretion of Ca and Pi. Our results showed that in newborn camels, Sr absorption test is simple, reproductible and may be used in exploration of intestinal Ca absorption.