The cyclohexene ring as bioisostere of a furanose ring: synthesis and antiviral activity of cyclohexenyl nucleosides.

Herdewijn P; De-Clercq E

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The cyclohexene ring as bioisostere of a furanose ring: synthesis and antiviral activity of cyclohexenyl nucleosides.

机译：作为呋喃糖环的生物等排体的环己烯环：环己烯基核苷的合成和抗病毒活性。

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摘要

The application of the bioisosteric concept between a furanose ring and a cyclohexene ring in the nucleoside field has led to the discovery of new potent antiviral agents.

机译：在呋喃糖环和环己烯环之间在核苷领域中应用生物立体异构概念已导致发现了新的有效抗病毒剂。

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《Bioorganic and Medicinal Chemistry Letters》 |2001年第12期|共7页
作者
Herdewijn P; De-Clercq E;
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原文格式 PDF
正文语种 eng
中图分类药学;生物化学;
关键词
cyclohexene; Ring; Nucleosides; 核苷类;

机译：cyclohexene;Ring;Nucleosides;核苷类;

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专利

1. The cyclohexene ring as bioisostere of a furanose ring: synthesis and antiviral activity of cyclohexenyl nucleosides. [J] . Herdewijn P, De-Clercq E Bioorganic and Medicinal Chemistry Letters . 2001,第12期

机译：作为呋喃糖环的生物等排体的环己烯环：环己烯基核苷的合成和抗病毒活性。
2. Synthesis and antiviral activity of a series of new cyclohexenyl nucleosides. [J] . Gu P, Morral J, Wang J, Antiviral chemistry & chemotherapy . 2003,第1期

机译：一系列新的环己烯基核苷的合成和抗病毒活性。
3. Synthesis and antitumour activity of new tiazofurin analogues bearing a 2,3-anhydro functionality in the furanose ring. [J] . Popsavin M, Spaic S, Svircev M, Bioorganic and Medicinal Chemistry Letters . 2007,第15期

机译：呋喃糖环中带有2，3-脱水官能团的新的tiazofurin类似物的合成和抗肿瘤活性。
4. SYNTHESIS AND NONLINEARITY OF TRIENE CHROMOPHORES CONTAINING THE CYCLOHEXENE RING STRUCTURE [C] . Symposium on electrical, optical, and magnetic properties of organic solid-state materials . 1998

机译：含环己烯结构的三烯发色团的合成与非线性
5. Synthesis of cyclo, ring expanded, and backbone extended nucleosides. [D] . Theile, Christopher Stone. 2012

机译：合成环，扩环和骨架扩展的核苷。
6. North- and South-Bicyclo3.1.0 Hexene Nucleosides. The Effect of Ring Planarity on Anti-HIV Activity [O] . Pamela L. Russ, Dr. Maria J. Gonzalez-Moa, Dr. B. Christie Vu, -1

机译：北方和南方自行车3.1.0己烯核苷。环平面性对抗HIV活性的影响
7. Metabolism of Drugs. XXX. The Biotransformation of Drugs having Cyclohexene Ring.(3). The Synthesis and Metabolism of 5-Ethyl-5-(1-cyclohexenyl)-4, 6-dioxohexahydropyrimidine [O] . Minoru Yoshimura, Hisao Tsukamoto 1962

机译：药物代谢。 XXX。具有环己烯环的药物的生物转化。（3）。 5-乙基-5-（1-环己烯基）-4,6-二氧杂环丁二嘧啶的合成和代谢

The cyclohexene ring as bioisostere of a furanose ring: synthesis and antiviral activity of cyclohexenyl nucleosides.

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