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首页> 外文期刊>Journal of addiction medicine >Buprenorphine and medication management in a community corrections population: a pilot study.
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Buprenorphine and medication management in a community corrections population: a pilot study.

机译:社区矫正人群的丁丙诺啡和药物管理:一项试点研究。

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This project sought to demonstrate the feasibility and acceptability of providing on-site buprenorphine treatment to individuals under community corrections supervision. Seventeen women and 13 men were enrolled on-site over a 2-week period at a community corrections location. Study participants received open-label study medication dispensed weekly over 12 weeks, weekly medication management therapy, and returned for a 1-month follow-up. Participants were predominantly female (56%) and white (90%) with an average age of 31.7 ± 7.4 years. More than half (53%) had hepatitis C virus infection and 75.9% reported intravenous use of opioids in the 30 days before treatment. Rates of illicit substance use was high, as 37.9% of urines were positive for benzodiazepines, 31.7% were positive for cocaine, and 13.7% were positive for alcohol across the time in the study. Although rates of positive urines for opiate use and sex with multiple partners did not change during treatment, rates of injection drug use significantly decreased during treatment. Overall, 86.7% of participants were retained through the 1-month follow-up with low rates of adverse events. Acceptability and feasibility of this approach were demonstrated by the ability to enroll and randomize the target sample of participants over 2 weeks with high retention and low rates of adverse events through 1-month follow-up. This pilot study demonstrated that this population could be successfully engaged in treatment and show reductions in risky behaviors. However, more intensive interventions may be needed to reduce opiate use to reach this vulnerable population at their point of contact with the criminal justice system.
机译:该项目旨在证明在社区矫正监督下向个体提供现场丁丙诺啡治疗的可行性和可接受性。在为期两周的活动中,共有17名女性和13名男性在社区矫正场所就读。研究参与者接受了为期12周的每周分配的开放标签研究药物,每周药物管理疗法,并返回进行了1个月的随访。参加者主要是女性(56%)和白人(90%),平均年龄为31.7±7.4岁。超过一半(53%)的患者感染了丙型肝炎病毒,有75.9%的患者报告在治疗前30天内静脉使用了阿片类药物。在整个研究过程中,非法物质的使用率很高,因为37.9%的尿液对苯二氮卓类药物呈阳性,可卡因呈阳性,占31.7%,酒精呈阳性,占13.7%。尽管在治疗期间阿片类药物使用的阳性尿液的比率以及与多个伴侣的性行为没有改变,但是在治疗期间注射用药的比率显着下降。总体而言,通过1个月的随访保留了86.7%的参与者,不良事件发生率较低。这种方法的可接受性和可行性通过在2个月内对参与者的目标样本进行登记和随机分组的能力得以证明,并通过1个月的随访获得了较高的保留率和不良事件发生率。这项初步研究表明,该人群可以成功地接受治疗,并且可以减少危险行为。但是,可能需要采取更强有力的干预措施,以减少鸦片制剂的使用,以便在与刑事司法系统接触的这一点使这一脆弱人群受益。

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