First case of New Delhi metallo-beta-lactamase 1-producing Escherichia coli infection in Japan.

摘要

To the Editor-Emergence of multi-drug-resistant organisms is a threat to public health, because there is limited effort devoted to the development of new antibiotics [1]. Multiple new mechanisms of resistance have been described recently, including a new type of carbapenem resistance gene, la_NDM_1 reported in 2009 [2]. Infections due to strains with bla_NDM_1 have been reported in India, Pakistan, the United Kingdom, and the United States [2-4].We report the first case, to our knowledge, of New Delhi metallo-beta lactamase 1 (NDM-l)-producing Es-cherichia coli infection in Japan. A 54-year-old Japanese man traveled to India for business in March 2009. During his trip, he developed dysarthria, blurring of his left eye, and tingling in his right upper extremity.