Can indole-based extracts prevent colorectal cancer via early apoptotic pathways?

摘要

Colorectal cancer (CRC) is the second most common cause of cancer-related death in the western world and is increasing in incidence in many Asian countries, coinciding with a shift to western style diets. Diet and lifestyle are the most important aetiological factors for CRC accounting for up to 70% of cases while fewer than 20% of cases are attributable directly to genetic causes.