Gamma-Irradiated Cross-Linked Polyethylene in Total Hip Replacements

摘要

The purpose of this study was to evaluate the mechanical and chemical characteristics of gamma-irradiated, cross-linked polyethylene after long-term service in vivo. Two gamma-irradiated ultra high molecular weight polyethylene (RCH 1000, molecular weight: 10~6) total hip replacement sockets were retrieved at 15 and 16 years after implantation. Mechanical and chemical characteristics of the sockets were evaluated in comparison with nonirradiated sockets. Significant surface oxidation occurred in the nonirradiated sockets; up to 75 percent of that seen in the irradiated ones. The mechanical properties of the irradiated sockets were not subject to increased deterioration in the presence of high free radical content. The cross-link was stable and was retained for a long period both in vivo and in ambient air. These data indicate that gamma-irradiated polyethylene was not subject to increased oxidative degradation during long-term service in vivo and confirmed the usefulness of this material as an articulating surface in total hip replacement.