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Nonlocal Effect on Stiffness Measurements of a Collagen Molecule

机译:胶原分子刚度测量的非局部效应

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Accurate modeling of collagen molecules including their stiffness is essential for our understanding of mechanics of collagen fibers and tissues where these fibers play a prominent role. Studies of mechanical properties of collagen molecules employing various experimental methods and molecular dynamics (MD) simulations yield a broad range of values of the modulus of elasticity. The effect of nonlocal elasticity on the molecule stiffness derived from experiments and simulations is assessed in this brief. The estimate of the correction accounting for the nonlocal effect utilizes the exact solution of the nonlocal elasticity theory for one-dimensional elastic bars. It is demonstrated that the effect of nonlocal elasticity on the stiffness of collagen molecules can be neglected.
机译:准确建模胶原分子(包括其刚度)对于我们理解胶原纤维和组织(其中这些纤维起着重要作用)的力学至关重要。使用各种实验方法和分子动力学(MD)模拟研究胶原分子的机械性能会产生很大范围的弹性模量值。在此简介中评估了非局部弹性对源自实验和模拟的分子刚度的影响。考虑到非局部效应的校正估计值利用了一维弹性杆的非局部弹性理论的精确解。结果表明,可以忽略非局部弹性对胶原分子刚度的影响。

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