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首页> 外文期刊>Journal of Biotechnology >Complete genome sequence of Bifidobacterium animalis subsp lactis KLDS 2.0603, a probiotic strain with digestive tract resistance and adhesion to the intestinal epithelial cells
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Complete genome sequence of Bifidobacterium animalis subsp lactis KLDS 2.0603, a probiotic strain with digestive tract resistance and adhesion to the intestinal epithelial cells

机译:动物双歧杆菌乳酸亚种KLDS 2.0603的完整基因组序列,该益生菌菌株具有消化道抗性并粘附于肠上皮细胞

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摘要

Bifidobacterium animalis subsp. lactis KLDS 2.0603 (abbreviated as KLDS 2.0603) is a probiotic strain isolated from the feces of an adult human. Previous studies showed that KLDS 2.0603 has a high resistance to simulated digestive tract conditions and a high ability to adhere to intestinal epithelial cells (Caco-2). These two characteristics are essential requirements for the selection of probiotic bacteria. To explore the stress resistance mechanism to the digestive tract environment and the adhesive proteins of this strain, in this paper, we reported the complete genome sequence of KLDS 2.0603, which contains 19,469 bp and encodes 1614 coding sequences(CDSs), 15 rRNA genes, 52 tRNA genes with 1678 open reading frames. (C) 2016 Elsevier B.V. All rights reserved.
机译:动物双歧杆菌亚种乳酸菌KLDS 2.0603(缩写为KLDS 2.0603)是从成年人粪便中分离出的益生菌菌株。先前的研究表明,KLDS 2.0603对模拟消化道条件具有很高的抵抗力,并且对肠上皮细胞(Caco-2)的粘附能力也很高。这两个特征是选择益生菌的基本要求。为了探索该菌株对消化道环境和黏附蛋白的抗逆机制,我们报道了KLDS 2.0603的完整基因组序列,该序列包含19,469 bp,编码1614个编码序列(CDS),15个rRNA基因,具有1678个开放阅读框的52个tRNA基因。 (C)2016 Elsevier B.V.保留所有权利。

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