Human liver-resident CD56(bright)/CD16(neg) NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways

Hudspeth Kelly; Donadon Matteo; Cimino Matteo; Pontarini Elena; Tentorio Paolo; Preti Max; Hong Michelle; Bertoletti Antonio; Bicciato Silvio; Invernizzi Pietro; Lugli Enrico; Torzilli Guido; Gershwin M. Eric; Mavilio Domenico

首页> 外文期刊>Journal of Autoimmunity >Human liver-resident CD56(bright)/CD16(neg) NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways

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Human liver-resident CD56(bright)/CD16(neg) NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways

机译：人肝驻留CD56（亮）/ CD16（阴性）NK细胞通过CCR5和CXCR6途径参与而保留在肝窦内

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Rationale: The liver-specific natural killer (NK) cell population is critical for local innate immune responses, but the mechanisms that lead to their selective homing and the definition of their functionally relevance remain enigmatic.

机译：原理：肝脏特异性自然杀伤（NK）细胞群体对于局部先天免疫反应至关重要，但是导致其选择性归巢的机制及其功能相关性的定义仍然是个谜。

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《Journal of Autoimmunity》 |2016年第null期|共11页
作者
Hudspeth Kelly; Donadon Matteo; Cimino Matteo; Pontarini Elena; Tentorio Paolo; Preti Max; Hong Michelle; Bertoletti Antonio; Bicciato Silvio; Invernizzi Pietro; Lugli Enrico; Torzilli Guido; Gershwin M. Eric; Mavilio Domenico;
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正文语种 eng
中图分类医学免疫学;
关键词
Liver immunology; Homing of hepatic NK cells; Cherokees Chemokine receptors;

机译：肝免疫学;肝NK细胞归巢;切诺基趋化因子受体;

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1. Human liver-resident CD56(bright)/CD16(neg) NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways [J] . Hudspeth Kelly, Donadon Matteo, Cimino Matteo, Journal of Autoimmunity . 2016,第Null期

机译：人肝驻留CD56（亮）/ CD16（阴性）NK细胞通过CCR5和CXCR6途径参与而保留在肝窦内
2. Dysfunction of CD3(-)CD16(+)CD56(dim) and CD3(-)CD16(-)CD56(bright) NK cell subsets in RR-MS patients [J] . Tahrali Ilhan, Kucuksezer Umut Can, Altintas Ayse, Clinical immunology: The official journal of the Clinical Immunology Society . 2018,第期

机译：CD3（ - ）CD16（+）CD56（DIM）和CD3（ - ）CD16（ - ）CD56（ - ）CD56（明亮的）NK细胞亚群体的功能障碍在RR-MS患者中
3. ENDOMETRIAL NK CELL SUBPOPULATIONS CD16(-)CD56(BRIGHT) AND CD16(-)CD56(DIM) IN WOMEN WITH RECURRENT IMPLANTATION FAILURE [J] . Stamenov Georgi, Penkova Kalinka, Chaushev Todor, Biotechnology & Biotechnological Equipment . 2013,第5期

机译：反复着床失败的女性子宫内膜NK细胞亚群CD16（-）CD56（亮）和CD16（-）CD56（DIM）
4. Musca domestica Larvae Lectin Induced Apoptosis in Human Breast Cancer MCF-7 Cells through ROS-JNK Mediated Caspase Pathway and ROS-Ca2;+ Pathway [C] . Wang Zhuo, Cao Xiao-hong, Hou Li-hua, 5th International Conference on Bioinformatics and Biomedical Engineering . 2011

机译：家蝇幼虫凝集素通过ROS-JNK介导的Caspase途径和ROS-Ca2; +途径诱导人乳腺癌MCF-7细胞凋亡
5. The functional role of the activating receptors TIM-3 and CD16 in human natural killer (NK) cell biology. [D] . Gleason, Michelle Kathleen. 2012

机译：激活受体TIM-3和CD16在人类自然杀伤（NK）细胞生物学中的功能作用。
6. Human liver-resident CD56bright/CD16neg NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways [O] . Kelly Hudspeth, Matteo Donadon, Matteo Cimino, -1

机译：人肝驻留CD56bright / CD16neg NK细胞通过CCR5和CXCR6途径参与而保留在肝窦内
7. Human liver-resident CD56^bright/CD16^neg NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways [O] . Hudspeth, Kelly, Donadon, Matteo, Cimino, Matteo, 2016

机译：通过CCR5和CXCR6通路的参与，人类肝驻留CD56 ^{/ CD16 ^{neg NK细胞被保留在肝窦内}}

Human liver-resident CD56(bright)/CD16(neg) NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways

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