The Modified Checklist for Autism in Toddlers: A Follow-upStudy Investigating the Early Detection of Autism SpectrumDisorders

摘要

Autism spectrum disorders (ASD) often goundetected in toddlers. The Modified Checklist for Autismin Toddlers (M-CHAT) was used to screen 3,793 childrenaged 16-30 months from low- and high-risk sources;screen positive cases were diagnostically evaluated. Re-screening was performed on 1,416 children aged 42-54 months. Time 1 Positive Predictive Value (PPV) was .36for the initial screening and .74 for the screening plusfollow-up telephone interview; values were similar forTime2 PPV. When separating referral sources, PPV waslow for the low-risk sample but acceptable with the follow-up telephone interview. Children with ASD from the low-risk and high-risk samples were highly similar. Resultsindicate that the M-CHAT continues to be a promisinginstrument for the early detection of ASD.