An investigation of cortical bone loss and fracture patterns in the neolithic community of Catalhoyuk, Turkey using metacarpal radiogrammetry

摘要

Bioarchaeologists have conducted numerous studies on human skeletal remains using metacarpal cortical bone radiogrammetry. This method allows cortical thickness of the second metacarpal to be quantified. As a sensitive index of bone health metacarpal cortical thickness is evaluated in the context of functional adaptations, growth, ageing and bone loss in osteoporosis, as well as used as a reliable indicator of fracture risk. The focus of this study is an examination of the widely used calculation that expresses second metacarpal cortical bone values, followed by an examination of age and sex-related patterns of cortical bone loss and skeletal fragility fracture in a Neolithic archaeological skeletal sample from Catalhoyuk, Turkey. Using metacarpal radiogrammetry, 49 adult metacarpals (f = 27 m = 22) were examined. Data were collected for size variables, length (L) and total bone width (TW) as well as quantity variables, medullary width (MW) and cortical thickness (CT). These parameters were then used to calculate the widely used cortical index (CI) and two new indices expressing medullary width and cortical bone thickness in relation to length (medullary width index, MWI and cortical thickness index, CTI). The ratios were then used to explore age- and sex-related cortical bone loss and fragility fracture patterns amongst the inhabitants of Catalhoyuk. Catalhoyuk males and females demonstrate an inverse relationship where CTI decreases as age and MWI increase. Analyses indicate statistically significant age-related change in MWI amongst the oldest females. Despite age-related loss of bone, no typical fragility fractures are observed. We discuss the role of ageing and lifestyle factors at Catalhoyuk that may have been beneficial to skeletal health and a reduction in the risk of fragility fracture.