Last Word on Point:Counterpoint: Pulmonary edema does not occur in human athletes performing heavy sea-level exercise.

摘要

We appreciate the interest and input of the accompanying commentaries (see Ref. 7). However, we wish to restate that this PoinfcCounterpoint is related to human athletes performing sea-level exercise. Reports of edema with exercise at altitude or breath-hold diving, while interesting, represent an entirely different physiological scenario and are not central to the present debate. Furthermore, we are puzzled by the arguments used by some of our colleagues to support the case of exercise-induced pulmonary edema. What is the actual published evidence that sea-level exercise produces pulmonary edema? In our Counterpoint (3) we presented a summary of the many unsuccessful attempts to document pulmonary edema and we raised serious methodological concerns over the few studies that claim to have detected evidence of edema. In our opinion, interpreting these studies as "proof of edema is based on an uncritical assessment of the collective data.