Nuclear magnetic resonance spectroscopy and mass spectrometry of solanidine, leptinidine, and acetylleptinidine. Steroidal alkaloids from Solanum chacoense Bitter.

摘要

Solanidine, leptinidine and acetylleptinidine from Solanum chacoense were structurally characterized by high-resolution mass spectrometry and high-field 1H-NMR (nuclear magnetic resonance) and 13C-NMR. 1H-NMR and 13C-NMR chemical shifts were assigned for solanidine and acetylleptinidine using DEPT, HMBC, and HMQC. Complete carbon chemical shift assignments are presented for all three alkaloids. The orientation of the C-23 acetoxyl group of acetylleptinidine was determined to be axial.