Cardiac Involvement in Myotonic Dystrophy Type 2 Patients With Preserved Ejection Fraction Detection by Cardiovascular Magnetic Resonance

摘要

Background-Myotonic dystrophy type 2 (DM2) is a genetic disorder characterized by skeletal muscle symptoms, metabolic changes, and cardiac involvement. Histopathologic alterations of the skeletal muscle include fibrosis and fatty infiltration. The aim of this study was to investigate whether subclinical cardiac involvement in DM2 is already detectable in preserved left ventricular function by cardiovascular magnetic resonance.