The study demonstrates an example of the law of diminishing returns when combining medical therapies for a condition. An analogous situation exists, for example, in management of hypertension. Four individual antihypertensive drugs may each have an effect in lowering blood pressure, but the combined effect of quadruple therapy would likely not be the sum of the individual effects, and would often be much less. The marginally greater effect size in the PRP group (21.7 vs 20.5 points), which reached neither statistical nor clinical significance, may reflect the same phenomenon. The role of PRP may be as an alternative treatment for resistant tendinopathy that fails to respond to eccentric loading, rather than as combination therapy.
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机译：这项研究展示了一个结合药物治疗某种疾病的收益递减规律的例子。类似的情况存在于例如高血压的治疗中。四种单独的降压药可能各自具有降低血压的作用，但是四联疗法的综合作用可能不会是个体作用的总和，并且通常要少得多。 PRP组稍大的效应量（21.7 vs 20.5分），既没有统计学意义也没有临床意义，可能反映了相同的现象。 PRP的作用可能是无法应对偏心负荷的抵抗性肌腱病的替代治疗，而不是联合治疗。
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