Prevalence of non-albicans Candida vaginitis in patients on hormonal treatment in Jabalpur, Central India

摘要

Objective. -The aim of this study was to compare the frequency of involvement Candida albicans and non-albicans Candida in patients on hormonal treatment with vulvovaginal candidiasis. Patients and methods. -In the present investigation, 81 women were screened for vulvovaginal infections, of which 43 (53.1%) were positive for Candida infections and four with other fungi. The total patients were categorized into two groups. The patients who had complaint of vaginitis but not taking any kind of other treatment were kept in control group (without hormone) and the patients who had complaint of vaginitis but on hormone treatment for infertility were kept in test group (hormone treated). Out of these 43 patients, 25 (58.2%) were receiving hormones as treatment for infertility or as support for pregnancy. Eighteen patients who had candidal vaginitis but not on the hormone treatment were kept as control group. Samples of vaginal discharge were collected by swab and inoculated onto Sabouraud dextrose agar chloramphenicol. The yeasts isolates were identified by conventional methods. Results. - The highest incidence of infection was found in age group 21-30 years (49%) followed by 31-40 years (37%). The frequency of VVC due to non-albicans Candida species was 64% as compared to 36% caused by C. albicans. In hormone treated group, among non-albicans Candida species highest incidence of vulvovaginitis was due to C. glabrata 06 (24%) followed by C. tropicalis 05 (20%), C. parapsilosis 02 (8%), C. krusei, C. vishwanathii and an unidentified non-albicans Candida species 01 each (4%). Conclusion. -The data highlights the emergence of non-albicans Candida infections among patients of vulvovaginal candidiasis (WC) in Jabalpur hospital (India).