Association between serum uric acid levels and cardiometabolic risk factors among Japanese junior high school students.

摘要

Hongo et al examined whether serum uric acid (SUA) levels were associated with cardiometabolic risk factors among Japanese junior high school students and concluded that SUA was strongly associated.1 They suggested that the measurement of SUA might be a useful health-screening test for school children. However, they did not examine the usefulness of SUA measurement in addition to the measurements of body mass index (BMI), waist circumference (WC), blood pressure (BP), fasting plasma glucose (FPG), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and total cholesterol. For this purpose, longitudinal studies regarding the incidence of metabolic syndrome (MetS), diabetes mel-litus (DM), and cardiovascular disease (CVD) are eventually necessary. In cross-sectional studies, at least the independent association of SUA with MetS, DM or CVD should be examined, adjusting for BMI or WC, BP, FPG, TG, and HDL-C. The measurement of SUA is not useful as a screening test if SUA is not associated with MetS independently of BMI, WC, BP, FPG, TG, and HDL-C.