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首页> 外文期刊>Circulation journal >How is combination therapy with ACEI and ARB applied in patients with acute myocardial infarction?
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How is combination therapy with ACEI and ARB applied in patients with acute myocardial infarction?

机译:急性心肌梗死患者如何应用ACEI和ARB联合治疗?

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摘要

Activation of the renin-angiotensin system (RAS) has a profound effect on the prognosis of patients with myocardial infarction and/or heart failure with reduced ejection fraction (HFREF), as proven by the beneficial effects of angiotensin-converting enzyme inhibitors (ACEIs). Because angiotensin II is produced in the ACE-dependent and -independent pathways, the addition of ATI receptor blockers (ARBs) to ACEIs is expected to completely block RAS activity and to improve the prognosis of patients with cardiovascular diseases.
机译:血管紧张素转换酶抑制剂(ACEIs)的有益作用证明,肾素-血管紧张素系统(RAS)的激活对心肌梗死和/或心力衰竭患者的射血分数(HFREF)降低有深远影响。 。由于血管紧张素II是通过ACE依赖性和非依赖性途径产生的,因此向ACEI中添加ATI受体阻滞剂(ARB)有望完全阻断RAS活性并改善心血管疾病患者的预后。

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