If nothing gets looked at...nothing changes.

摘要

Darier disease (DD) is an autosomal dominant slcin disorder because of mutations in the gene ATP2A2. Two segmental forms of the disease have been distinguished. Type 2 manifestations are veiy infrequent. To date, the coexistence of band-like areas of excessive and absent involvement has been reported only once.A 50-year-old man presented with a chronic slcin disorder involving the trunk, face and limbs, which had begun at the age of 12 years. The lesions had appeared on the ears and buttocks. Over the years, they had tent to generalize and became confluent. He complained of moderate itching and malodor. The disease worsened in summer. The diagnosis of DD had been established in another centre at the age of 28, and the patient had been taken oral retinoids since then with a poor response. He had no family history of DD.