Practice of Interferon Therapy Chronic hepatitis C (Therapy with consensus interferon)

摘要

The consensus interferon, rlFN-alphaconl, has been proved to be effective for the treatment of chronic hepatitis C (CH-C) with genotype 1b and high viral load (>=100 kc/ml) through randomized controlled studies performed in Japan. For patients with genotype 1b and high viral load, the complete response rate (16.7%) of rlFN-alphaconl (18MU) is significantly higher than that of IFN-na (6MU), though it is 0% in those with a viral load of more than 700 kc/ml. rlFN-alphacon1 is also effective for the treatment of CH-C patients with both low viral load and a history of prior IFN treatment. It will be concluded that rlFN-alphaconl is effective for CH-C patients with a viral load of less than 700kc/ml.