A simple, convenient and effective method for the synthesis of dibenz(B,F) 1,4-oxazepines(CR); A new generation, riot control agent and its analogues

摘要

A new synthetic route has been developed for the synthesis of seven membered heterocyclic ring dibenz (b, f) 1,4-oxazepine (CR) starting with condensation of o-aminophenol and o-chlorobenzaldehyde followed by salt formation and cyclisation in DMSO at 120 degrees C. The method has been extended for the preparation of other substituted dibenzoxazepines.