SYNTHESIS AND CHARACTERIZATION OF 4-SUBSTITUTED l-(4-HALOGENOPHENYL)PYRROLIDIN-2-ONES WITH AZOLE AND AZINE MOIETIES

摘要

4-Substituted l-(4-fluoro-and 4-chlorophenyl)pyrrolidin-2-ones containing azole, oxadiazole, triazole, and triazine fragments have been synthesized, and the characterization of the obtained products is presented. The study compounds have been analyzed by elemental analysis, and the NMR, IR, MS techniques. The ~1H/~(13)C 2D (HETCOR), APT (~(13)C) NMR methods, and molecular modeling (MM2) were used for structure elucidation in more complicated cases.